What types of environmental factors or exposures might cause a male patient to be tested for sterility. How do these factors affect the production or health of sperm?

What types of environmental factors or exposures might cause a male patient to be tested for sterility. How do these factors affect the production or health of sperm?
What role does estrogen play in the onset of menopause? What are the benefits of producing estrogen for women’s health? What are the risks of continued estrogen  production after menopause?

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